Changes between Version 10 and Version 11 of Communication/Publications/2020


Ignore:
Timestamp:
Jun 5, 2020, 7:33:24 AM (4 years ago)
Author:
td1719
Comment:

--

Legend:

Unmodified
Added
Removed
Modified

  • Communication/Publications/2020

    v10 v11  
    77 Abstract
    88
    9  The ‘Laser-hybrid Accelerator for Radiobiological Applications’, LhARA, is conceived as a novel uniquely-flexible facility dedicated to the study of radiobiology. The technologies demonstrated
    10 in LhARA, which have wide application, may be developed to allow particle-beam therapy to be delivered in a completely new regime, combining a variety of ion species in a single treatment
     9 The ‘Laser-hybrid Accelerator for Radiobiological Applications’, LhARA, is conceived as a novel uniquely-flexible facility dedicated to the study of radiobiology. The technologies demonstrated in LhARA, which have wide application, may be developed to allow particle-beam therapy to be delivered in a completely new regime, combining a variety of ion species in a single treatment
    1110fraction and exploiting ultra-high dose rates. LhARA will be a hybrid accelerator system in which laser interactions drive the creation of a large flux of protons or light ions that are captured using
    1211a plasma (Gabor) lens and formed into a beam. The laser-driven source allows protons and ions to be captured at energies significantly above those that pertain in conventional facilities, thus
    … …  
    1413new regimes, delivering protons and light ions in a wide variety of time structures, spectral distributions, and spatial configurations at instantaneous dose rates up to and significantly beyond
    1514the ultra-high dose-rate ‘FLASH’ regime.
    16  It is proposed that LhARA be developed in two stages. In the first stage, a programme of in-vitro experiments will be served with proton beams with energies between 10 MeV and 15 MeV. In stage two, the beam will be accelerated using a fixed-field accelerator (FFA). This will allow experiments to be carried out in vitro and in vivo with proton beam energies of up to 125 MeV. In
    17 addition, ion beams with energies up to 30 MeV per nucleon will be available for in-vitro an in-vivo experiments. This paper presents the conceptual design for LhARA and the R&D programme by
    18 which the LhARA consortium seeks to establish the facility.
     15 It is proposed that LhARA be developed in two stages. In the first stage, a programme of in-vitro experiments will be served with proton beams with energies between 10 MeV and 15 MeV. In stage two, the beam will be accelerated using a fixed-field accelerator (FFA). This will allow experiments to be carried out in vitro and in vivo with proton beam energies of up to 125 MeV. In addition, ion beams with energies up to 30 MeV per nucleon will be available for in-vitro an in-vivo experiments. This paper presents the conceptual design for LhARA and the R&D programme by which the LhARA consortium seeks to establish the facility.
    1916
    2017----