= '''WP4 Meeting with the Project Office''' =
''02 September 2021'' 

Timeline for Project:


2 yr 	design and simulate for LhARA  stage 1: 12MeV in – vitro expts. Standard dish puts bragg peak in cell layer – hence 15MeV target to give ‘headroom’


5 yr 	build for LhARA stage 1. in – vitro expts by biologists proof of principal.
Clinical system is longer term. 5+ yrs


TPrice
•	the 36MeV system in Birmingham produces tracks with bragg peak at approx – 13mm of water.
•	12-15MeV tracks will be shorter  ~few mm in water. 
[[span(style=color: #FF0000, How could one resolve the peak in such a short track? )]]

•	Requires high resolution –which in turn requires high frequencies. 
•	Requires different sensors from higher energy system. 
From this we conclude 
•	Lots of challenges for a low energy system. 
•	Low energy test does not de-risk the high energy system.

[[span(style=color: #FF0000,What spatial resolution does the map need to be useful to biologists )]] – **Action CW**: to contact JP to ask. 

[[span(style=color: #FF0000, Does the photoacoustic system with high resolution offer advantages for ‘mini-beam’?)]]

Discussion surrounding alternative to BHam and Cern sources @ intermediate energy.
•	Medical places are usually 100’s MeV and long pulse. 
•	TPrice Daresury AVO. 4 stage project – could have been within 2 years – short sharp pulses. **Action TP**: to contact AVO
•	Surrey synchrotron – low energy. 
•	60MeV Clatterbridge. 30mm penetration.
•	Clinical centres struggle to get below 70MeV with cyclotrons and dose rate is low.
•	Conclude there are no alternatives – apparently LhARA will indeed be unique.

Group concludes:

2 activities are required
 
1.	LhARA consortium proves it has capability to detect a signal – can use any source. This is not a world first, but necessary.
2.	12-15MeV system design – LhARA phase 1 needs a diagnostic Phase 1 will run for 5-10 years

Should simulate beams at low energies. **Action KL**: to adjust C++ code
Mechanics of system are also a subject for discussion.