LhARA Project WPM Meeting 20th February 2024 14:00 GMT = Meeting URL: ​https://strath.zoom.us/j/84550543598?from=addon Meeting ID: 845 5054 3598 Password: 737274 ------------------------------------------- = Agenda == Bridging funds === K Long - discussion - slides ([raw-attachment:01-2024-02-20-Long1.pptx here]) Bridging funds. Uniform 'tax.' across all WP - 6% ([raw-attachment:1st_Cost24_02_20_CW2.xlsx here]) Milestones === Radiobiological Science and technology Work Package 7: • M7.1: Develop beamline and bespoke facilities at SCAPA for radiobiology experimentation M30 • M7.2: Preliminary results from cell survival/DNA damage experiments with laser-accelerated protons at SCAPA M36 • M7.3: Development of RBEs of laser-accelerated protons (versus pre-existing cyclotron-driven protons) in established cell lines M48 • M7.4: Assessment of DNA damage repair kinetics and immunopeptidomic analysis of laser-accelerated protons M48 Work package 4: Ion-acoustic dose mapping • M4.3: Iterative reconstruction methods M42 • M4.4: Integration: ultra-sonic array with radiobiology station M48 ''' may require manpower up-lift and some equipment funds • M4.5: LhARA ion-acoustic test results M48 Work package 5: Novel end-station development • M5.4: Construct transportable beam delivery end-station M42. • M5.6: Report on LhARA stage 1 beam monitoring system M48. Plus numerical studies to interpret ans evaluate experimental programme - Student led. === ITRF/LhARA Facility R&D Stage. 1 TDR Work package 2: Laser-driven proton and ion source • M2.3: Investigation and demonstration of 10 Hz debris and damage challenges at ICL M36 • M2.4: Demonstration of continuous operation of 1 Hz beam generation on SCAPA M48 Work package 3: Proton and ion capture • M3.3: Progress report on increased voltage penning trap simulations and operation. M36 • M3.4: Final report high voltage penning trap operation. M48 Work package 0 & 6: Design and integration • M6.2: Final review of R&D work towards LhARA Phase 1 TDR M42 Stage 2 CDR • M6.3: Review of R&D work towards LhARA Phase 2 CDR M48 === Management === Work Package 0 & 1. Project management: Deliverables plus internationalisation • D5 Initial progress review TDR & technical de-risk update M30 • D6 Interim progress review TDR & technical de-risk update M36 • D7 Final progress review TDR & technical de-risk update M42 • D8 Stage 1 TDR & technical de-risk report M48 Work Package 8: • Creation of collaborative international clinical research group M40 • Wider public engagement - All party parliamentary group on radiotherapy M48 == PA1 === Achievements - humble bragg competition? == AOB