LhARA Project WPM Meeting 20th February 2024 14:00 GMT = Meeting URL: ​https://strath.zoom.us/j/84550543598?from=addon Meeting ID: 845 5054 3598 Password: 737274 ------------------------------------------- = Agenda == Bridging funds === K Long - discussion - slides ([raw-attachment:01-2024-02-20-Long1.pptx here]) Bridging funds. Uniform 'tax.' across all WP - 6% ([raw-attachment:1st_Cost24_02_20_CW2.xlsx here]) Milestones === Radiobiological Science and technology Work Package 7: • ''' M7.1: Develop beamline and bespoke facilities at SCAPA for radiobiology experimentation M30 ''' • ''' M7.2: Preliminary results from cell survival/DNA damage experiments with laser-accelerated protons at SCAPA M36 ''' • ''' M7.3: Development of RBEs of laser-accelerated protons (versus pre-existing cyclotron-driven protons) in established cell lines M48 ''' • ''' M7.4: Assessment of DNA damage repair kinetics and immunopeptidomic analysis of laser-accelerated protons M48 ''' Work package 4: Ion-acoustic dose mapping • ''' M4.3: Iterative reconstruction methods M42 ''' • ''' M4.4: Integration: ultra-sonic array with radiobiology station M48 ''' may require manpower up-lift and some equipment funds • ''' M4.5: LhARA ion-acoustic test results M48 ''' Work package 5: Novel end-station development • ''' M5.4: Construct transportable beam delivery end-station M42. ''' • ''' M5.6: Report on LhARA stage 1 beam monitoring system M48. ''' Plus numerical studies to interpret ans evaluate experimental programme - Student led. === ITRF/LhARA Facility R&D Stage. 1 TDR Work package 2: Laser-driven proton and ion source • ''' M2.3: Investigation and demonstration of 10 Hz debris and damage challenges at ICL M36 ''' • ''' M2.4: Demonstration of continuous operation of 1 Hz beam generation on SCAPA M48 ''' Work package 3: Proton and ion capture • ''' M3.3: Progress report on increased voltage penning trap simulations and operation. M36 ''' • ''' M3.4: Final report high voltage penning trap operation. M48 ''' Work package 0 & 6: Design and integration • ''' M6.2: Final review of R&D work towards LhARA Phase 1 TDR M42 ''' Stage 2 CDR • ''' M6.3: Review of R&D work towards LhARA Phase 2 CDR M48 ''' === Management === Work Package 0 & 1. Project management: Deliverables plus internationalisation • ''' D5 Initial progress review TDR & technical de-risk update M30 ''' • ''' D6 Interim progress review TDR & technical de-risk update M36 ''' • ''' D7 Final progress review TDR & technical de-risk update M42 ''' • ''' D8 Stage 1 TDR & technical de-risk report M48 ''' Work Package 8: • ''' Creation of collaborative international clinical research group M40 ''' • ''' Wider public engagement - All party parliamentary group on radiotherapy M48 ''' == PA1 === Achievements - humble bragg competition? == AOB