Changes between Initial Version and Version 1 of Research/LhARA/RadiationBiology/Meetings/2025-06-12


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Timestamp:
Jun 12, 2025, 4:15:54 PM (2 weeks ago)
Author:
ccd24
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  • Research/LhARA/RadiationBiology/Meetings/2025-06-12

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     1= LhARA radiobiology; meeting: 12Jun25; 14:00 BST =
     2
     3**Present:** CW, CD, RW, RG, TP, JP, JMcG, EM, DO, HO
     4
     5== Notes ==
     6
     71. //[wiki:Research/LhARA/RadiationBiology/Meetings/2025-05-29 Minutes and actions]: //
     8
     92. //Field mapping, preparation of PMQs: // HO/BS \\
     10 - Delivery today (12th June) Fingers crossed
     11
     123. //Strathclyde Updates: // RG, RW, CW \\
     13 - Laser optics have been damaged:
     14  - Hope for company to come and replace the Sapphire crystal by next week (Wednesday...). Require testing time for the new laser, and likely the quad testing will have to be pushed back to July.
     15  - Investigate if ITRF can extend funding. Otherwise bio run will have to be done before September. (There is a potential clash with a Czech experiment as well).
     16 - Drives and stands to be delivered next week. Robbie has everything prepped, so this should not cause a delay.
     17 - Bio-safety cabinets' exhausts could be fixed by 19th June:
     18  - Back-up would be a cabinet on the 5th floor. Colin to talk to the person who uses that, but no rush to use since there is the delay due to the laser and this cabinet is a recirculating one, so not as sterile as desired.
     19 - Waste and plastic consumables:
     20  - Birmingham to order them and pay. Delivery to Strathclyde. Waste disposal needs coordination and might require someone to be trained at Strathclyde.
     21 - RCF stack fiduciary:
     22  - Use a laser to cut a fiduciary
     23  - Maybe send to Chris for cutting (Keep Ken and Calvin in the loop).
     24
     254. // PMQ Positioning: // CD, RG, JMcG \\
     26 - Inspected off-energy particles using a uniform energy source distribution. Distribution for a 2cm diameter spot size peaks near 10MeV and has tails on either side. Higher energy tail expected to decrease when the uniform spectrum is replaced by an laser-driven one. Spot size diameter corrected to 1.85cm.
     27 - Calvin to pass on the energy distributions to Tony to simulate the dose on the cells.
     28 - Simulation structure: 50 micron deep mylar vacuum window. 2.5 micron deep mylar covering the cells. Cells usually 20-40 microns deep in the media.
     29
     30
     315. //Simulation update: // KL, CD \\
     32 - No update
     33
     346. //Bioprep: // EM/MH \\
     35 - Next cyclotron run on Thursday (19th Jun)
     36
     37
     389. DoNM
     39 - 19Jun25 14:00 **BST**
     40 - Check with Ross and Robbie to confirm if the laser has caused a delay
     41
     4210. AoB \\
     43
     44=== Summary of actions ===
     45 - **CD**: Send energy distributions to Tony in csv or txt format
     46 - **HO**: Flag the laser delay with ITRF and ask for a possible extension
     47 - **CW**: Check on exhausts and talk to the "owner" of the backup cabinet
     48 - **RW/RG**: Fix the laser :) and cut fiduciary into RCF stacks
     49 - **BT/RW**: Send Calvin the proton energy spectrum.
     50 - Something with consumables and waste???
     51
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     53
     54
     55----