= LhARA radiobiology; meeting: 02Oct25; 14:00 BST = **ZOOM:** https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1 **Present:** CD, EM, JP, DA, AFr, TP, TP(Jnr), RW, MH, JMcG, KL == Agenda == 1. Minutes and actions: - **CD**: Upload Technical Summary - **Done** - **MH**: Send Calvin the CAD of the cell carousel - **Done** - **DA**: Investigate increasing Mylar window thickness - **Done** - **JP**: Consumables plan - **Done** - **CW**: Check service and testing of hoods - **Stands?** - **JMcG/KL**: Remove old calendar invites - **Done** - **KL/CD**: Update angular divergence in LLO - **Stands** 2. Strathclyde : BT, ED, RW \\ - Processing the RCF from Phase 1 - All the RCF scanned on the relevant scanner now - Calvin, Nick and Robbie to meet to discuss - Robbie to send the RCF data to Tony as well - he can calculate the calibration curve - Once we understand the dose: - Organise Robbie, Emma and Jason to discuss irradiation plan - Alter PMQ/target mounts - ~5cm closer after moving the mounts - Add position referencing systems to PMQ drives - Robbie has built this in - Install cell rotation mount - Fine alignment and checking rotation works correctly still to be done - Further updates: - TP now setup to switch on quite quickly. Can pump it down easily 3. Simulation CD, DA, AFr: \\ - Results of an Au foil in the beamline - Mean dose drops by a factor of 10 minimum - Diaza to sample transverse distribution at several points along the beamline - Source production to be improved - Calvin to investigate defocussing the quads further - Practicality of implementing a scattering foil - For Biology - Reduced mean dose only a problem if still aiming to do FLASH - Physically - SCAPA have an arm to use to place the foil in - The simplest position is in the vacuum tube (or maybe entry to tube) - Robbie to provide the viable positions of the foil in the beamline for simulations - Can obtain 10um Gold easily (Goodfellas) - Chris Spindloe to be the help if the transverse size needs to be reduced down 4. BioPrep EM, JP: \\ - Dry-run - Delayed due to hood availability - To be done at the beginning of the actual run. - Should not cause a delay to the actual run if the dry run cannot be completed - Dates for actual run - 27th Oct - 21st Nov - Emma on annual leave 24th to 31st Oct - Jason tied up on the week of 10th. Might be available on week of 3rd. - Dates can be pushed back if necessary - Plan for run - First week is obtaining proton focus again - Next two weeks is irradiation 5. Beam Diagnostics KL, CD: \\ - Show RCF holder idea - Could do with something to fix the holder to the cell carousel - Robbie and Calvin to sit down and discuss this - Ken update on a sparse beam diagnostic - Jessel Patel is a good man to talk to at RAL about this - Ken going to chase Chris and try and find money too 6. DoNM - 16th October 7. AoB - Tony's baby has officially joined LhARA! === Summary of actions === - **CD/RW/ND**: Meet to discuss RCF calibration - **RW**: Send TP RCF data - **RW**: Fine tune installation of cell carousel - **DA**: Sample simulated beamline more frequently - **CD**: Investigate defocussing to improve uniformity - **CD/RW**: Design RCF holder - **KL**: Discuss sparse diagnostic at CLF ----