= LhARA radiobiology; meeting: 23Oct25; 14:00 BST =

**ZOOM:** https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1 

Attended: CD, EM, AFr, KL, JMcG, CW, TP

== Meeting Notes == 

1. Minutes and actions:
- **RW**: Fine-tune installation of cell carousel
 - **Stands**
- **RW:** Send proton numbers to Tony to get the dose rate
 - **Done**
- **CD/DA/Afr:** Find final beam setup with gold foil
 - **Stands**
- **CD:** Find alternative 8MeV setup
 - **Done**
- **EM/JMcG/DA/more visitors:** Complete the online training indicated by Mark
 - **Stands**
- **CW/RW:** Turn on and clean the water in the incubators
 - **Stands**
- **CW:** Contact Marie Boyd
 - **Done** Waiting
- **RW:** Add lip to RCF holder
 - **Stands**

2. Strathclyde: BT, ED, RW \\
- Dose rate updates
 - Tony and Calvin to meet with Robbie to sort this out. Invite Nick Dover as well
- Fine-tune carousel
- Incubator not turned on yet
 - Colin offered to sort it; just needs access 

3. Simulation CD, DA, AFr: \\
- Results of 8MeV setup
 - 8MeV requires smaller drifts, but there are some values that fall into an acceptable range.
 - [raw-attachment:10MeV_vs_8MeV.pptx Slides]
- Priority is to achieve a high dose, uniformly across the dish. Uniformity needs to be no more than 10%. Also must be uniform across the depth of the dish too, so no Bragg peaks, which means no protons entering the media with less than 1MeV.
- Set up optimisation to find the best setup to achieve this.

4. BioPrep EM, JP: \\
- Finalised irradiation plan
 - [raw-attachment:Glasgow_Cell_Plan.docx Plan]
- Confirmation of plan for staining cells - when and who is needed
 - Need to have someone available on the 14th to do staining from the 5th.
 - Contact Diaza about whether he will be available
 - Contact Robbie about clearing people for weekend work in case clonogenics are done on the Thursday or Friday
 - For the clonogenic cells in the third week Emma will stain these and then bring them back to Birmingham
 - Cannot be done on the 28th so clonogenics on the third week should be aimed for Tuesday, the 18th Nov
- Marie Boyd has been contacted but no response

5. Beam Diagnostics KL, CD: \\
- RCF update
 - Trying to get as much done as possible at Imperial with Kevin
- Lip on RCF holder 
 - No update
- Real-time beam diagnostic 
 - Lanex cannot be placed around the cell dish as previously hoped. No room to fit the camera in.

6. DoNM 
- Next Week: 30th Oct

7. AoB
- Confirm everyone has filled out the sheet and confirmed they are visiting
 - Link to the sheet: https://docs.google.com/spreadsheets/d/13vkixxNBZX42WFtxw7_MFJTU-gc06J19N8zpTcMKFys/edit?usp=sharing
 - Ken to determine visiting dates
 - Emma to fill out sheet but has completed training
- Visitors complete the online training indicated by Mark

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=== Summary of actions ===
- **CD/DA/Afr:** Find final beam setup with gold foil
- **Visitors:** Complete the online training indicated by Mark
- **CW/RW:** Turn on and clean the water in the incubators
- **RW:** Add lip to RCF holder
- **RW/TP/CD:** Meet to discuss dose rate calculation. Tony to send an email for the meeting time.
- **DA:** Confirm availability for staining
- **CD:** Confirm possibility of completing staining at the weekend
- **CD:** Fine-tune run plan for first week and fill out details from irradiation plan
- **KL/CD:** Get RCF cut