LhARA radiobiology; meeting: 05Mar26; 14:00 BST

ZOOM: ​https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1

Meeting Agenda

0. Short Recap of In-Person

1. BioPrep

• Updates:
  • EM: Present bio plan
• Actions:
  • EM: Write up a biology plan
    • Decide whether to use Marie's lab and whether to stick with HeLa
  • EM, MB, JP, RA: Meet to finalise details
  • Unassigned: Obtain an inverted microscope

2. Simulations

• Updates:
  • Josie to present the latest BO results on finding the optimal beamline
  • BELLA Paper

3. SCAPA Beamline

• Updates:
  • Quick look at Robbie's master's student's work on variation in the energy spectrum and the dose variation

4. In-Beam Diagnostic

• Updates:
  • General?

5. DoNM
   • 19th Mar 14:00

6. AoB

Summary of actions required

In-Beam Diagnostics

• RW, CD: Study correlation between laser diagnostics and mean dose
• CD, TP: Refine evaluations of LET in the cells with the RCF in front
• CD: Predict the cell dish dose from the RCF in front of it
• PH: Investigate how to get the light out of the vacuum chamber
• Investigate how a phosphor sheet could be incorporated into the design
• Acquire a glass sheet

Bio Next Steps

• EM: Write up a biology plan
  • Decide whether to use Marie's lab and whether to stick with HeLa
• EM, MB, JP, RA: Meet to finalise details
• Unassigned: Obtain an inverted microscope

Improve the spatial variation

• CD, JMcG: Investigate how to achieve uniformity without a scatterer in place

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