| | 1 | = LhARA radiobiology; meeting: 23Jul26; 14:00 GMT = |
| | 2 | |
| | 3 | **ZOOM:** https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1 |
| | 4 | |
| | 5 | == Agenda == |
| | 6 | |
| | 7 | 1. General Discussion |
| | 8 | - Robbie mentioned that beamtime might be more likely in February. |
| | 9 | - Colin believes we might be able to get some time in Autumn if we can time it correctly with other beamtime. |
| | 10 | - There is work where the SCAPA team are using AI and looking at the variability of the laser. |
| | 11 | - Colin to discuss with Robbie how to build the setup with another experiment |
| | 12 | |
| | 13 | 2. Instrumentation |
| | 14 | - General |
| | 15 | - Colin suggested filling the carousel and running 1 shot then repeating with 2 shots etc |
| | 16 | - Each cell dish would have Lanex around it or something for real-time measurement |
| | 17 | - Then we could skip the calibration stage by comparing the variation in the Lanex signal with the known variation in dose |
| | 18 | - Problems involve the number of cells needing to be collected and the time that would take |
| | 19 | - Needs discussion with bio team |
| | 20 | - SciFi |
| | 21 | - Need to actually test whether the transporting fibre will scintillate |
| | 22 | - Operate on the assumption it does not |
| | 23 | - If it does Peter has ordered hollow-fibre |
| | 24 | - Might be able to use a standrad fibre-optic connector |
| | 25 | - ICT |
| | 26 | - Colin has ICTs |
| | 27 | - 3-5ns rise time, so should see the short pulses but on the edge of visible and may be blurred out |
| | 28 | - 0.1V in signal per Amp in beam current |
| | 29 | - Beam would also need to be roughly symmetric, so has to be after the scatterer |
| | 30 | - There is also a smaller, more sensitive ICT we could use |
| | 31 | - Also possibilities with 3D printing |
| | 32 | |
| | 33 | 3. Overview of Trello |
| | 34 | - Reminder plan is laid out in the google doc and can be changed |
| | 35 | - Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar |
| | 36 | - Planning next SCAPA Document: https://docs.google.com/document/d/1OTARVtxhLRu02S6CLdRDB2QlGvCqDfZ3aWBifjIFs_Q/edit?usp=sharing |
| | 37 | |
| | 38 | 4. DoNM |
| | 39 | - 23/07/26 |
| | 40 | |
| | 41 | 5. AoB |
| | 42 | |
| | 43 | |
| | 44 | === Summary of actions required === |
| | 45 | |
| | 46 | In-Beam Diagnostics |
| | 47 | - **Unassigned**: Acquire a glass sheet |
| | 48 | - **Unassigned**: Get a new RCF batch and calibrate |
| | 49 | - **TP**: Testing delaminating EBT3 |
| | 50 | - **PH**: Obtain transparent fibre or an alternative method for light transport |
| | 51 | - **PH**: Obtain a lens for hollow fibre tests |
| | 52 | - **CD**: Simulate energy deposited in transport fibres |
| | 53 | - **KL, CD, JMcG, PH**: Design a system to make full scifi prototypes |
| | 54 | - **KL, CD, JMcG, PH**: Make a full scifi prototype |
| | 55 | - **KL, CD, JMcG, PH**: Discuss visit to Birmingham to test SciFi |
| | 56 | - **RW, CD**: Study the correlation between laser diagnostics and mean dose |
| | 57 | - **Unassigned**: Investigate how a phosphor sheet could be incorporated into the design of the cell dish |
| | 58 | - **CW**: Investigate the feasibility of ICTs for our beamline |
| | 59 | |
| | 60 | Bio Next Steps |
| | 61 | - **EM, CD, JMcG**: Write up technical summary of Phase 2 |
| | 62 | - **EM**: Write up a biology plan for a 2 PMQ setup |
| | 63 | - **Unassigned**: Obtain an inverted microscope |
| | 64 | - **Unassigned**: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's) |
| | 65 | - **Unassigned**: Obtain a thermostat for the incubator |
| | 66 | - **MB, JP, MB**: Meet up to plan cell survival dry run and a bio plan for a 2 Quad setup |
| | 67 | - **EM**: Run controls to examine how long the cells can survive vertically |
| | 68 | |
| | 69 | Beamline Modelling |
| | 70 | - **CD**: Examine energy spectra variation |
| | 71 | - **RW, CD**: Source characterisation |
| | 72 | |
| | 73 | Alternate Beamlines |
| | 74 | - **JMcG**: Simulate BELLA |
| | 75 | - **JMcG**: Simulate ELI |
| | 76 | |
| | 77 | ---- |
