= LhARA Radiobiology Meeting: 06Aug26; 14:00 BST =

**ZOOM:** https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1 

- Planning Document: https://docs.google.com/document/d/1OTARVtxhLRu02S6CLdRDB2QlGvCqDfZ3aWBifjIFs_Q/edit?tab=t.0

- Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

== Meeting Notes == 

1. BioPrep
- Josie: Summary of last week's biology meeting:
 - Bio plan being prepped short- and long-term, covering both experiments within our existing collaboration remit and ways to expand the team/bring in outside experts. 
 - Jason and Emma have mapped internal biological experiments comparing radiation source results from cells to organoids to animals (see Emma's RAL lecture). 
 - Plan to hold a seminar day with the wider field to showcase LhARA, discuss overlapping work, and identify partners suited to joining LhARA or collaborating. 
 - Further meetings needed to nail down specifics for both the seminar and near-term experiments.

2. Instrumentation
- RCF:
 - Tony investigated delaminated EBT3 as a thinner alternative for dosimetry (minimal dose interference) but couldn't source it. Discussed manufacturing our own instead. 
 - Marie flagged that Alexander Mullen works on polymer thinning/stretching — plan to meet him to discuss making a thin sheet to sit in front of the cells without significantly reducing dose. 
 - Also agreed to reach out to NPL: Richard G. will connect with Giuseppe to discuss their similar process. 
 - Richard also mentioned the benefit in looking at fast electrons and will report back findings at the next meeting.
- Scifi:
 - Unlikely to get clear fibre to Robbie before he goes to ELI and want to test it at Birmingham first
 - Equipment currently at Queen Mary's (Ken talking to them)
- Air Scintillation
 - Colin/Narendar: Planning to meet to discuss the feasibility of the implementation at SCAPA and the timeframe 

3. SCAPA
- Team busy- no updates this week

4. Alternate Beamlines
 - No ELI feedback yet

5. Review Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

6. DoNM 
 - 20/08/26

7. AoB 

=== Summary of actions required ===

In-Beam Diagnostics
- **Unassigned**: Acquire a glass sheet
- **Unassigned**: Get a new RCF batch and calibrate
- **TP**: Testing delaminating EBT3
- **PH**: Obtain transparent fibre or an alternative method for light transport
- **PH**: Obtain a lens for hollow fibre tests
- **CD**: Simulate energy deposited in transport fibres
- **KL, CD, JMcG, PH**: Design a system to make full scifi prototypes
- **KL, CD, JMcG, PH**: Make a full scifi prototype
- **KL, CD**: Send clear fibre to SCAPA before 16th August (Contact Ewan or Colin since Robbie is USA)
- **KL, CD, JMcG, PH**: Discuss visit to Birmingham to test SciFi
- **RW, CD**: Study the correlation between laser diagnostics and mean dose
- **Unassigned**: Investigate how a phosphor sheet could be incorporated into the design of the cell dish
- **CW**: Investigate the feasibility of ICTs for our beamline
- **MH**: Investigate LET detector
- **CW**: Ask Narender about air fluorescence implementation
- **JMcG**: Investigate using IF as a dosimeter


Bio Next Steps
- **EM, CD, JMcG**: Write up technical summary of Phase 2
- **EM**: Write up a biology plan for a 2 PMQ setup
- **Unassigned**: Obtain an inverted microscope
- **Unassigned**: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's)
- **Unassigned**: Obtain a thermostat for the incubator
- **EM**: Run controls to examine how long the cells can survive vertically
- **JMcG**: Plan a test of vertical cell survival using Emma/Jason's HeLa cell line and Marie's cell line
- **JMcG**: Produce a HeLa colony that can survive on Mylar

Beamline Modelling
- **Unassigned**: Investigate how to improve the beamline beyond CV=8%
- **CD**: Examine energy spectra variation
- **RW, CD**: Source characterisation

Alternate Beamlines
- **JMcG**: Simulate BELLA
- **JMcG**: Simulate ELI

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