LhARA Radiobiology Meeting: 17Sep26; 14:00 BST

ZOOM: ​https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1

• Planning Document: ​https://docs.google.com/document/d/1OTARVtxhLRu02S6CLdRDB2QlGvCqDfZ3aWBifjIFs_Q/edit?tab=t.0

• Trello: ​https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

Meeting Agenda

1. Alternate Beamlines
   • ELIMED part of the next ELI submission?
   • Template document put together for how to deal with problems raised in ELI rejection

2. BioPrep
   • Update from Rosh and Marie
     • Any cells from Birmingham?
   • Colin seen the X-ray machine yet?
   • Perodi Paper (Flacco et al) with RCF sandwich: 10.1038/s41598-025-01105-z

3. Instrumentation
   • RCF
     • Updates on delaminated EBT4
   • SciFi
     • Introducing Simon
     • Update on next prototype
   • Fast electrons

4. Beamline Simulations

5. SCAPA
   • Updates

6. Review Trello: ​https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

7. DoNM
   • 01/10/26

8. AoB

Summary of actions required

In-Beam Diagnostics

• Unassigned: Acquire a glass sheet
• Unassigned: Get a new RCF batch and calibrate
• TP: Testing delaminating EBT3
  • DONE?
• PH: Obtain transparent fibre or an alternative method for light transport
  • DONE
• PH: Obtain a lens for hollow fibre tests
  • DONE
• CD: Simulate energy deposited in transport fibres
• KL, CD, JMcG, SdL: Design a system to make full scifi prototypes
• KL, CD, JMcG, SdL: Make a full scifi prototype
• KL, CD, JMcG, SdL: Discuss visit to Birmingham to test SciFi
• RW, CD: Study the correlation between laser diagnostics and mean dose
• CW: Investigate the feasibility of ICTs for our beamline
• MH: Investigate LET detector
• CW: Ask Narender about air fluorescence implementation
• JMcG: Investigate using IF as a dosimeter
• GS, RH: Investigate fast electron diagnostic
• TP: Investigating commerical delaminated EBT4

Bio Next Steps

• EM, CD, JMcG: Write up technical summary of Phase 2
• EM: Write up a biology plan for a 2 PMQ setup
• Unassigned: Obtain an inverted microscope
• Unassigned: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's)
• Unassigned: Obtain a thermostat for the incubator
• EM: Send cells to Rosh and Marie
• EM, MB, RA, JMcG: Run controls to examine how long the cells can survive vertically
• CW, AM: Show Alex around SCAPA
• MB, RA: Send specifications of and transwells to Tony to test at Birmingham
• MB, RA: Test transwells with x-rays
• KL: Share paper with interesting cell dishes (RCF sandwich)

Beamline Modelling

• Unassigned: Investigate how to improve the beamline beyond CV=8%
• CD: Examine energy spectra variation
• JMcG, ED: Discuss spectra fits and SCAPA source divergence
• JMcG: Talk to Darsebury to get more information on sensible dipole parameters

Alternate Beamlines

• JMcG: Simulate BELLA
• JMcG: Simulate ELI
• CD: Planning doc for ELI

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