= LhARA Radiobiology Meeting: 01Oct26; 14:00 BST = **ZOOM:** https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1 - Planning Document: https://docs.google.com/document/d/1OTARVtxhLRu02S6CLdRDB2QlGvCqDfZ3aWBifjIFs_Q/edit?tab=t.0 - Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar Attended: KL, MH, CW, TP, SdL, PB, RH, RA, FA, CD == Meeting Notes == 1. Alternate Beamlines - ELIMED part of the next ELI submission - There appear to be calls for ELIMED every year - 20th October 12:00 (noon) - Unlikely to make this deadline - Cannot make a submission repeating the same missing details - BUT: - **Calvin to share the document** - **Ken and Josie to nudge the bioplan into action** 2. BioPrep - Alex seen SCAPA - Yes and transwells have been agreed to be the best way forward - Transwells - Cost ~£1000 - February puts the bio team on a timetable - Need a stronger bio/SCAPA presence at these meetings - **Colin to reach out to Marie** - **Colin to reach out to the SCAPA team to confirm February is our goal** 3. Instrumentation - RCF - Updates on delaminated EBT4 - No longer sold unless for 100 boxes or more - Need 35 more boxes to get an order - Mark found a different type of film - Tony has requested a free sample to check it out - Tony has two master's students on cmos and can compare to the new film - SciFi - Construction pad is built - Appears to be no sensitivity to rotation of the array (as expected) - Thin wall ion chamber - On-line detector uses protons - Thin window (10s of um of Mylar) - Concern is mainly recombination at the time of ionisation because of the intense pulse - Will still see a residual ionisation - Diamond detector - Off-line using the electrons - Need a better understanding of the electrons to understand its feasibility - **Richard to discuss thin wall detectors and diamond detectors at a Tuesday meeting** - Calorimeter - Measure the energy by measuring the temperature change in graphite - Most stable and understood measure of dose - If we had £10K can ask the same company NPL asked to make a transcal detector thin enough for our energies - Sam Flynn's detector that has been discussed before - Longer term benefit is thatthey're known compared with something like air fluoresence which is not as well known - Further discussion: - Need to group these diagnostics into: - In-beam beamline diagnostics - Dosimetry run at the same time as cells. Measuring the dose in the cells. eg ion-acoustic - Measuring the dose of the low-energy beams to establish stability - As always, beamtime available in Birmingham - **Ken, Simon, Calvin and Josie to discuss next week** 4. SCAPA - Updates - No update 5. Review Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar 6. DoNM - 15/10/26 7. AoB - Funds - Have £5k - Ken meeting this afternoon to discuss £14k Imperial money === Summary of actions required === In-Beam Diagnostics - **Unassigned**: Acquire a glass sheet - **Unassigned**: Get a new RCF batch and calibrate - **SdL**: Simulate energy deposited in transport fibres - **KL, CD, JMcG, SdL**: Design a system to make full scifi prototypes - **KL, CD, JMcG, SdL**: Make a full scifi prototype - **KL, CD, JMcG, SdL**: Discuss visit to Birmingham to test SciFi - **RW, CD**: Study the correlation between laser diagnostics and mean dose - **CW**: Investigate the feasibility of ICTs for our beamline - **MH**: Investigate LET detector - **CW**: Ask Narender about air fluorescence implementation - **JMcG**: Investigate using IF as a dosimeter - **GS, RH**: Investigate fast electron diagnostic - **TP**: Investigating commerical delaminated EBT4 Bio Next Steps - **EM, CD, JMcG**: Write up technical summary of Phase 2 - **EM, MB, RA, JMcG**: Write up a biology plan for a 2 PMQ setup - **Unassigned**: Obtain an inverted microscope - **Unassigned**: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's) - **Unassigned**: Obtain a thermostat for the incubator - **EM**: Send cells to Rosh and Marie - **EM, MB, RA, JMcG**: Run controls to examine how long the cells can survive vertically - **CW, AM**: Show Alex around SCAPA - **MB, RA**: Send specifications of and transwells to Tony to test at Birmingham - **DONE** - **MB, RA**: Test transwells with x-rays - **KL**: Share paper with interesting cell dishes (RCF sandwich) - **DONE** Beamline Modelling - **Unassigned**: Investigate how to improve the beamline beyond CV=8% - **DONE** - **CD**: Examine energy spectra variation - **JMcG, ED**: Discuss spectra fits and SCAPA source divergence - **JMcG**: Talk to Darsebury to get more information on sensible dipole parameters - **DONE** Alternate Beamlines - **JMcG**: Simulate BELLA - **JMcG**: Simulate ELI - **CD**: Planning doc for ELI ----