= Nuclear diagnostics and MRI: 3^rd^ and 4^th^ year option course = == Outline == [raw-attachment:PhysicsMedicalImagingNuclearDiagnosticsandMRI2020-21.pdf Module outline presented at May 2020 options fair] \\ [raw-attachment:NDnMRI-overview.pdf Module overview prepared as introductory handout] == Overview == The course will run in the spring term from 15^th^ February to 26^th^ March 2021 and will be presented "online" in a mixture of asynchronous, pre-recorded "blocks" and synchronous "question and application" sessions. The more "theoretical" content be delivered in the form of topic-specific mini lectures augmented by "active learning" online, e.g. "quizzes", mini literature-review projects, and problems. This material will be prepared by the lecturer (Ken Long) and course associate (Ruth McLauchlan) and released weekly by the Physics Undergraduate Office. The synchronous content will address the practical application of the nuclear medicine and MRI techniques in the clinic. This material will be presented by practising medical physicists experts in the various field. Contributions will be made by Kuldip Nijran and Rebecca Quest from the Imperial College Healthcare NHS Trust and Sonia Nielles Vallespin from the National Heart and Lung Institute. The synchronous content will be delivered in "Question and application" (Q&A) sessions. There will be two of these sessions each week; the first on Wednesdays at 11:00 and the second on Fridays at 14:00. Each Q&A session will include protected time allocated for the students to raise questions related to any of the material presented in the course. Two problem sheets will be issued during the course, the first in week 3, the second in week 7. Assessment will be 100% by exam. The exam will be based on the asynchronous taught content and the material presented in the Q&A sessions. == Asynchonous content == || ** Week ** || ** Lecture ** || ** Section ** || ** "Active learning" ** || || 1. 15Feb21 || 1. [raw-attachment:Wk01-Lctr01.pdf Introduction, nuclear medicine o/v, nuclear decay theory] || 1. [raw-attachment:Wk01-Lctr01-Sctn01.pdf Introduction] || || || || || 2. [raw-attachment:Wk01-Lctr01-Sctn02.pdf Nuclear medicine] || || || || || 3. [raw-attachment:Wk01-Lctr01-Sctn03.pdf Nuclear decay, revision] || || || || 2. [raw-attachment:Wk01-Lctr02.pdf Radionuclides, production methods, gamma-camera intro] || 1. [raw-attachment:Wk01-Lctr02-Sctn01.pdf Radionuclides for nuclear medicine] || || || || || 2. [raw-attachment:Wk01-Lctr02-Sctn02.pdf Methods for production of radionuclides] || || || || 3. [raw-attachment:Wk01-Lctr03.pdf The gamma camera] || 1. [raw-attachment:Wk01-Lctr03-Sctn01.pdf Introduction] || || || || || 2. [raw-attachment:Wk01-Lctr03-Sctn02.pdf Gamma camera] || || || || || 3. [raw-attachment:Wk01-Lctr03-Sctn03.pdf Collimator] || || || || || 4. [raw-attachment:Wk01-Lctr03-Sctn04.pdf Scintillator] || || || || || 5. [raw-attachment:Wk01-Lctr03-Sctn05.pdf Examples] || || || 2. 22Feb21 || 4. [raw-attachment:Wk02-Lctr04.pdf Single photon emission computed tomography] || 1. [raw-attachment:Wk02-Lctr04-Sctn01.pdf Introduction] || || || || || 2. [raw-attachment:Wk02-Lctr04-Sctn02.pdf Reconstruction] || || || || || 3. [raw-attachment:Wk02-Lctr04-Sctn03.pdf Attenuation correction] || || || || || 4. [raw-attachment:Wk02-Lctr04-Sctn04.pdf Scattering correction] || || || || || 5. [raw-attachment:Wk02-Lctr04-Sctn05.pdf Examples] || || || || 5. [raw-attachment:Wk02-Lctr05.pdf Positron emission tomography I] || 1. [raw-attachment:Wk02-Lctr05-Sctn01.pdf Principles of positron emission tomography] || || || || || 2. [raw-attachment:Wk02-Lctr05-Sctn02.pdf System resolution] || || || || || 3. [raw-attachment:Wk02-Lctr05-Sctn03.pdf Sensitivity] || || || 3. 01Mar21 || 6. [raw-attachment:Wk03-Lctr06.pdf Positron emission tomography II] || 1. [raw-attachment:Wk03-Lctr06-Sctn01.pdf Types of coincidence event] || || || || || 2. [raw-attachment:Wk03-Lctr06-Sctn02.pdf System resolution] || || || || || 3. [raw-attachment:Wk03-Lctr06-Sctn03.pdf Data acquisition] || || || || || 4. [raw-attachment:Wk03-Lctr06-Sctn04.pdf Comparison of sensitivity and corrections] || || || || || 5. [raw-attachment:Wk03-Lctr06-Sctn05.pdf Examples] || || || || 7. [raw-attachment:Wk03-Lctr07.pdf Introduction to MRI and quantum-mechanical foundations] || 1. [raw-attachment:Wk03-Lctr07-Sctn01.pdf Introduction to MRI] || || || || || 2. [raw-attachment:Wk03-Lctr07-Sctn02.pdf Quantum mechanical foundations] || || || 4. 08Mar21 || 8. [raw-attachment:Wk04-Lctr08.pdf Classical development of principles of MRI] || 1. [raw-attachment:Wk04-Lctr08-Sctn01.pdf Classical derivation of Larmor equation] || || || || || 2. [raw-attachment:Wk04-Lctr08-Sctn02.pdf Rotating the magnetisation] || || || || || 3. [raw-attachment:Wk04-Lctr08-Sctn03.pdf Free induction decay] || || || || 9. [raw-attachment:Wk04-Lctr09.pdf Determination of T1 and T2] || 1. [raw-attachment:Wk04-Lctr09-Sctn01.pdf Determination of the spin-lattice relaxation time, T1] || || || || || 2. [raw-attachment:Wk04-Lctr09-Sctn02.pdf Determination of the spin-spin relaxation time, T2] || || || 5. 15Mar21 || 10. [raw-attachment:Wk05-Lctr10.pdf Magnetic Resonance Imaging: spatial localisation] || 1. [raw-attachment:Wk05-Lctr10-Sctn01.pdf Slice selective excitation] || || || || || 2. [raw-attachment:Wk05-Lctr10-Sctn02.pdf Encoding spatial information in k-space] || || || || || 3. [raw-attachment:Wk05-Lctr10-Sctn03.pdf Encoding spatial information into net magnetisation] || || || || 11. [raw-attachment:Wk05-Lctr11.pdf Magnetic Resonance Imaging: contrast] || 1. [raw-attachment:Wk05-Lctr11-Sctn01.pdf Spin-echo sequence for proton-density weighted image] || || || || || 2. [raw-attachment:Wk05-Lctr11-Sctn02.pdf Spin-echo sequence for T1-weighted image] || || || || || 3. [raw-attachment:Wk05-Lctr11-Sctn03.pdf Spin-echo sequence for T2-weighted image] || || || || || 4. [raw-attachment:Wk05-Lctr11-Sctn04.pdf Inversion recovery] || || || 6. 22Mar21 || 12. [raw-attachment:Wk06-Lctr12.pdf Magnetic Resonance Imaging: artefacts] || 1. [raw-attachment:Wk06-Lctr12-Sctn01.pdf Image formation in MRI, reprise] || || || || || 2. [raw-attachment:Wk06-Lctr12-Sctn02.pdf Aliasing (wraparound) and truncation artefacts; Gibbs phenomenon] || || || || || 3. [raw-attachment:Wk06-Lctr12-Sctn03.pdf Random motion artefacts] || || || || 13. [raw-attachment:Wk06-Lctr13.pdf More MRI artefacts] || 1. [raw-attachment:Wk06-Lctr13-Sctn01.pdf MRI artefacts: periodic motion] || || || || || 2. [raw-attachment:Wk06-Lctr13-Sctn02.pdf MRI artefacts: chemical shift] || || == Exam -- "Timed remote assessment" == [raw-attachment:ESOGE.2020.55-TRA-Guide.pdf Guidance provided by the Physics UG office] ----