BioPhysicsX meeting; 27Mar23; 08:00

Present: AG, CJ, KL, IMcN, PP

Notes

1. News and updates: KL, All
   • CIO "Charged Particles for Cancer Therapy":
     • Constitution finalised. Will be submitted this week.
   • Imperial strategy consultation:
     • Qualtrix input:
       • Required by 31Mar23. KL and IMcN will coordinate their input.
       • KL/IMcN considering submitting "one pager" outlining ambitions for LhARA, LhARA initiative, and potential for multidisciplinary institute.
   • Planning round:
     • KL has submitted paragraph of input to Physics planning round submission. IMcN considering submitting "matching" paragraph.
   • CNRS:
     • KL invited as part of "Brady party" to make presentation on LhARA (initiative) at meeting at CNRS HQ in Paris on 03/04Apr23.
     • Possible link between IRL and White City activity.

2. BioPhysicsX two-pager: CJ, All
   • Version 0.3
   • Discussion included the following pointers:
     • Need sentences at the beginning to place the initiative/institute in context;
     • Probably good idea to explain the breadth of the LhARA collaboration; 4-nations UK, international, Institut Curie in particular;
     • Need to emphasis key links with FOM/IC NHS H/c Trust (IMcN), OIRO (AG);
     • Add link to clinical applications: trials, transformation in clinical practice as ambition;
     • Line of sight to clinic; the "why" big picture;
     • Potential for spin-offs;
       • IBA, Hitachi, Mitsubishi, Procure: system-level potential for tie up with medical-equipment provider
       • Instrumentation and computing as incremental/long-term impact plan, and, no-loss theorem; valuable even if LhARA should fail.
     • Biological impact:
       • In particular, unique potential to provide capability to investigate "spatial/temporal impact of beams at very high doses"

• We agreed that bullet level inout would be provided to CJ as follows:
  • IMcN: Pre-clincal/clinical facing aspects of institute initiative
  • PP: I/p on delivering "a new, novel, big, different thing"
  • AG: I/p on biology and capability for radiation biology

3. Actions and next steps: All
   • Update on two pager, ideally this week.

4. DONM
   • In a month's time.

5. AoB

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