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LhARA radiobiology; meeting: 14Jul25; 14:00 BST
Present: CW, RW, CP, EM, JMcG, AFR, CD, KL, DA
Notes
- Minutes and actions:
- JP: Talk to Fisher and get a plan of action for the order and delivery of consumables to Strathclyde
- STANDS
- CD/AFR: Complete verification of RCF stack
- STANDS
- JP: Talk to Fisher and get a plan of action for the order and delivery of consumables to Strathclyde
- Strathclyde Updates: RW, CW
- Laser damage and beamtime:
- Damage also includes a vacuum pipe that needs fixing, defines a new schedule
- New Schedule:
- Week 1: Get back to where we were a month ago with correct laser delivery to the target.
- Week 2: Re-establish and troubleshoot proton generation.
- Week 3: Work with the quads and some diagnostic testing in the PoPLaR configuration.
- Opportunity for a full bio walkthrough.
- Double check the autoclave waste
- Highly dependent on week 1 and week 2
- Bio-safety cabinets:
- Recalibration still required and unsure of schedule
- RCF stack fiduciary:
- Smaller stack proving to be tricky
- Larger stack can be used as a viable back-up
- Ken may be able to encourage CLF to help with smaller stack
- Aligned with a cross-hair on carousel and a laser along the beam axis
- Laser damage and beamtime:
- Bioprep: EM/MH
- IF needs staining from the last experiments (14 vs 28 MeV)
- Issue with Mylar remains - colony survival too variable to be reliable
- Tested post-plating FaDu cells from Mylar following 28 MeV protons (0-4Gy) with reliable and consistent colony formation
- To do - Rerun cyclotron test experiments comparing 14 and 28 MeV with post-plating method for both HeLa and FaDu - date TBD
- To do - stain, image and analyse IF on Mylar
- DoNM
- 22Jul25 14:00 BST (After Work Package Manager meeting)
- Zoom Link: https://strath.zoom.us/j/81329354716
- Meeting ID: 813 2935 4716
- Password: 206483
- AoB
- Present work to LhARA fortnightly tomorrow
- CD: Updated SCAPA schedule
- EM: Updates from latest experiment
- CD: LMU work
- Present work to LhARA fortnightly tomorrow
Summary of actions
EM: Comparison of 14 and 28 MeV with post-plating method. Analyse IF on Mylar
CW: Bio-cabinets need recalibration
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