LhARA radiobiology; meeting: 26Jun25; 14:00 BST

Present: CW, RW, RG, HO, CP, EM, JMcG, AFR, CD

Notes

1. Minutes and actions:
   • CW: Check on exhausts and talk to the "owner" of the backup cabinet
     • DONE
   • BT/RW: Send Calvin the proton energy spectrum.
     • STANDS
   • JP: Talk to Fisher and get a plan of action for the order and delivery of consumables to Strathclyde
     • STANDS
     CW: Speak to autoclave facility for bio waste disposal.
     • DONE

2. Strathclyde Updates: RG, RW, CW
   

• Laser damage and beamtime:
  • No major update.
• Still on for July run.
  • Characterising the source to begin ~the week of the 14Jul
  • Quad alignment and set up to be from 22Jul - 25Jul (21Jul is a bank holiday)
    • Include cell sample for this run.
  • Funding can extend until end of the financial year.
    • Need to change the times of no-cost extensions (Emma to chase Tony about this).
  • Bio phase to occur after September

• Bio-safety cabinets
  • Fixed!
  • Recalibration to be completed in the next week

• Waste and plastic consumables:
  • Plan confirmed to use the autoclave in the Wolfson building.
    • Need to train someone to carry the waste over.
    • Marie Boyd is the back up.
  • No update from Jason as off, but had been contacted by Marie.
• RCF stack fiduciary:
  • Larger stack cut and notched
  • Smaller stack more tricky.
  • Can send to Rutherford for laser cutting

3. Field mapping, preparation of PMQs: HO/BS
   
   • Everything delivered or on delivery to Strathclyde.
   • Expected by Monday (30Jun)
   • Marked with a sharpie to indicate which way is forward.
     • F quad has the lettering the right way around when placed correctly in beamline.

4. PMQ Positioning/Beam optimisation: CD, RG, JMcG
   
   • Tony produced simulations with an average of 5.6KeV/um
   • Previous simulations of 10MeV had shown an average of 4.8KeV/um
   • Waiting for overlay from Tony to better understand distribution of LET

5. Simulation update: KL, CD
   
   • G4 simulation of RCF stacks complete.
   • Verified with SRIM and in comparison with LLO.
   • Does not show the splitting effect that was hoped for
   • Further verification with TOPAS simulating an RCF stacks

6. Bioprep: EM/MH
   
   • Cultures appeared to have survived.
   • Results will be ready before the next meeting

9. DoNM
   • 10Jul25 14:00 BST

10. AoB
    
    • Ross' last meeting :(

Summary of actions

• All the elements for the beamline are now in place
• TP (and others?): Chase up no-cost extensions
• RW: Cut and notch smaller RCF stack
• TP: Overlay previous LET distribution on newer
• CD/AFR: Verify G4 RCF stack

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