LhARA radiobiology; meeting: 28May26; 14:00 GMT

ZOOM: ​https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1

Meeting Agenda

1. Overview of desired paper and required aims for next SCAPA beamtime
   • Dates: July/August

Mark timepix to do some alpha work and could test LET at SCAPA OSLs

2. Steps before next beamtime and discussion

3. Discussion of aims post-October
   • Anything we can do in the next beamtime to build towards these

4. Aims for ELI
   • Thanks to Emma for coordinating the bid
   • Rough dates?

5. Quick updates
   • In-beam diagnostic
     • PH: Presentation on hollow fibre readout plan

Plastic silicone fibre with a hollow (vacuum/air) core and Peter has ordered some. 1m away gets 0.08% but any bending will decrease that substantially Ordered 1.6mm. Get 0.14% at ~1m of hollow fibre. Pass through a 10mm chunk of glass. Got a black box lens from manufacturer for correct simulation. Start with this for experiment and then decide on which size we actually need for optimised travelling Beinding does need to be fixed! Losses can be bent to the pwoer

• Bioprep
• SCAPA

6. Trello
   • Review: ​https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

7. DoNM
   • 11/06/26

bbi Josie can only find 68MeV particles (high energy) information. Robbie to ask him.

8. AoB

Summary of actions required

In-Beam Diagnostics

• Unassigned: Acquire a glass sheet
• Unassigned: Get a new RCF batch and calibrate
• PH: Investigate how to get the light out of the vacuum chamber
• CD: Simulate energy deposited in transport fibres
• KL, CD, JMcG, PH: Make a full scifi prototype
• KL, CD, JMcG, PH: Discuss visit to Birmingham to test SciFi
• RW, CD: Study correlation between laser diagnostics and mean dose
• Unassigned: Investigate how a phosphor sheet could be incorporated into the design of the cell dish

Bio Next Steps

• EM, CD, JMcG: Write up technical summary of Phase 2
• EM: Write up a biology plan for a 2 PMQ setup
• Unassigned: Obtain an inverted microscope
• Unassigned: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's)
• MB, JP, MB: Meet up to plan cell survival dry run
• EM: Run controls to examine how long the cells can survive vertically

Beamline Modelling

• RW: Examine energy spectra variation
• RW, CD: Source characterisation

Other Beamlines

• JMcG: Simulate BELLA
• JMcG: Simulate ELI

---