| | 13 | - Got rejected for several reasons but most are things we can deal with and the evaluators were generally positive and encouraged resubmission |
| | 14 | - Next proposals for ELI have a deadline in October |
| | 15 | - Beamtime next year |
| | 16 | - Ken checking whether ELIMED is part of that |
| | 17 | - Calvin to make a planning document so we can list the challenges and fill out how we will deal with them |
| | 18 | - Discuss with ELI instrumentation team to make acceptance as likely as possible |
| | 19 | - Discussion on beam energy |
| | 20 | - Marie and Rosh have done a gap analysis and found one looking at <10MeV protons |
| | 21 | - Fear that focussing on lower energy will not appeal to ELI since they have the technology to reach 60MeV |
| | 22 | - ELI also appears to have lower beam quality as you go to lower energy |
| | 23 | - Jason has comparison at Clatterbridge for 60MeV and 28MeV |
| | 24 | - Could suggest higher energies but also no clear indication that lower energy was a reason we got rejected since we did not mention beam energy in the original submission |
| 15 | | - Updates |
| | 27 | - Ken and Josie did a review |
| | 28 | - Ken showed a figure showing cell death and very little difference between laser-driven and conventional but also multi-pulse and single shots |
| | 29 | - Aim should be to improve on this |
| | 30 | - Rosh and Marie have done a gap analysis |
| | 31 | - They need to get the cells from Birmingham to start doing tests on transwells and the carousel |
| | 32 | - Rosh has started defrosting cells |
| | 33 | - They have also started looking at clever cell dish designs |
| | 34 | - Ken found one with RCF sandwiched in between that he will send over to them |
| | 35 | - Transwells are made for certain sizes: 12mm or 24mm |
| | 36 | - 12mm would make more sense for us |
| | 37 | - Requires at least 3 replicates |
| | 38 | - Marie to test this with the x-ray irradiator |
| | 39 | - Investigate if they get enough cells |
| | 40 | - Smaller dish also means more beam to use for instrumentation |
| | 41 | - Need a technical document on the transwells as well |
| | 42 | - Marie to send specifications of the transwells to Tony. |
| | 43 | - Send some to Birmingham so Tony (Emma) can test the transwells there as well. |
