Changes between Version 1 and Version 2 of Research/LhARA/RadiationBiology/Meetings/2026-09-17


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Timestamp:
Sep 17, 2026, 3:35:05 PM (33 hours ago)
Author:
ccd24
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  • Research/LhARA/RadiationBiology/Meetings/2026-09-17

    v1 v2  
    77- Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar
    88
    9 == Meeting Agenda ==
     9Attended: CD, KL, TP, RH, JMcG, SdL, MH, AFr, TG
     10
     11== Meeting Notes ==
    1012
    11131. Alternate Beamlines
    1214 - ELIMED part of the next ELI submission?
     15  - YES
     16 - There appear to be calls for ELIMED every year
    1317 - Template document put together for how to deal with problems raised in ELI rejection
    1418
    15192. BioPrep
    16  - Update from Rosh and Marie
    17   - Any cells from Birmingham?
    18  - Colin seen the X-ray machine yet?
    1920 - Perodi Paper (Flacco et al) with RCF sandwich: 10.1038/s41598-025-01105-z
     21 - Check where the transwells are being delivered to
     22 - Preliminary analysis on using a 12mm diameter suggests CV drops below 5%, so technically no further beamline adjustment is necessary if the transwells at this size work.
    2023
    21243. Instrumentation
    2225 - RCF
    2326  - Updates on delaminated EBT4
     27   - Requested a quote and Ben Phoenix will buy a box, so should have some soon
     28 - Ben asked for a calibration of EBT3
     29  - Cal to send Tony as a zip
     30  - Alfredo will also have a look and see if he has the scans
    2431 - SciFi
    25   - Introducing Simon
    26   - Update on next prototype
    27  - Fast electrons
     32  - Simon is a Master's student who will join us till the end of February and will focus on the scifi array
     33  - There are spare days in November for use of the Cyclotron
     34  - We should book those and we can test the scifi there
     35  - Can also test the transwell setup with scifi around the edge
     36  - If nothing else can test a bundle of clear fibre to see if it scintillates
     37  - Tony can match our variation in beam, as long as there is enough time to simulate it beforehand and get the right scatterer
     38  - If it does scintillate, could remove that light by using a filter since the scintillation light from the transport fibre and the scintillation light from the array will have different wavelengths.
     39 - Fast electrons (Richard's and Giuseppe's notes)
     40  - Electrometer
     41   - With enough time, could be manually controlled between pulses
     42   - Measure off-axis
     43  - XDS Oxford IC SPEC
     44   - Thin-windowed ion chambers
     45   - £20K (maybe get on loan)
     46   - 20um thick
     47  - Giuseppe's Notes: The windowless chamber that I was thinking of, is an extrapolation chamber that determines absorbed dose by measuring the ionisation produced in a very small air cavities while varying the electrode separation and extrapolating the collected charge to zero cavity thickness (i.e. at the entrance of the chamber which is where the cells will be). However, for very low-energy proton beams, the proton range may be comparable to the cavity dimensions and the energy deposition can vary strongly over very short distances. Consequently, the extrapolation procedure would not work since the method relies on the assumption that the charged-particle fluence and dose distribution remain approximately uniform across the cavity.
     48 - Need a better understanding of the electron to proton distribution
    2849
    29 4. Beamline Simulations
     504. Review Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar
    3051
    31 5. SCAPA
    32  - Updates
    33 
    34 6. Review Trello: https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar
    35 
    36 7. DoNM
     525. DoNM
    3753 - 01/10/26
    3854
    39 8. AoB
     556. AoB
    4056
    4157