| | 1 | = LhARA radiobiology; meeting: 14May26; 14:00 GMT = |
| | 2 | |
| | 3 | **ZOOM:** https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1 |
| | 4 | |
| | 5 | == Meeting Agenda == |
| | 6 | |
| | 7 | Plan for PoPLaR |
| | 8 | 1. Next SCAPA beamtime |
| | 9 | - Dates: |
| | 10 | - Determine a baseline/default |
| | 11 | - Steps required for a better repeat of cell irradiations |
| | 12 | - Google doc summary and Trello |
| | 13 | |
| | 14 | 2. Aim for results for October and beyond |
| | 15 | - What papers? |
| | 16 | - What changes are required to that baseline plan for SCAPA to achieve that by October |
| | 17 | |
| | 18 | 3. ELI |
| | 19 | - Dates? |
| | 20 | - How does this fit into the plan |
| | 21 | |
| | 22 | 4. Review steps required |
| | 23 | - Share Trello |
| | 24 | |
| | 25 | 5. DoNM |
| | 26 | - 28/05/26 |
| | 27 | |
| | 28 | 6. AoB |
| | 29 | - IPAC submitted |
| | 30 | |
| | 31 | === Summary of actions required === |
| | 32 | |
| | 33 | In-Beam Diagnostics |
| | 34 | - **RW, CD**: Study correlation between laser diagnostics and mean dose |
| | 35 | - **CD, TP**: Refine evaluations of LET in the cells with the RCF in front |
| | 36 | - **CD**: Predict the cell dish dose from the RCF in front of it |
| | 37 | - Initial measurements of sci-fi arrays |
| | 38 | - Provide plan for Master's students who will count photons from UV source for sci-fi arrays |
| | 39 | - **PH**: Investigate how to get the light out of the vacuum chamber |
| | 40 | - **Unassigned**: Investigate how a phosphor sheet could be incorporated into the design of the cell dish |
| | 41 | - **Unassigned**: Acquire a glass sheet |
| | 42 | |
| | 43 | Bio Next Steps |
| | 44 | - **EM**: Write up technical summary of Phase 2 |
| | 45 | - **EM**: Write up a future biology plan |
| | 46 | - Decide whether to use Marie's lab and whether to stick with HeLa |
| | 47 | - **EM, MB, JP, RA**: Meet to finalise details |
| | 48 | - **CD**: Gather ideas for improving cell survival |
| | 49 | - **Unassigned**: Obtain an inverted microscope |
| | 50 | - **Unassigned**: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's) |
| | 51 | - **Unassigned**: Run controls to examine how long the cells can survive vertically |
| | 52 | |
| | 53 | Improve the spatial variation |
| | 54 | - Decide the energy we should be optimising for |
| | 55 | - **RW**: Examine energy spectra variation |
| | 56 | - **CD**: Find LET for different energies in the cell dish |
| | 57 | - **DONE** |
| | 58 | |
| | 59 | Other Beamlines |
| | 60 | - **JMcG**: Simulate BELLA |
| | 61 | - **JMcG**: Talk to ELI people and simulate ELI |
| | 62 | - **EM**: Coordinate ELIMED bid |
| | 63 | |
| | 64 | ---- |