| 1 | LhARA Project WPM Meeting 20th February 2024 14:00 GMT = |
| 2 | |
| 3 | Meeting URL: https://strath.zoom.us/j/84550543598?from=addon |
| 4 | |
| 5 | Meeting ID: 845 5054 3598 Password: 737274 |
| 6 | |
| 7 | ------------------------------------------- |
| 8 | |
| 9 | = Agenda |
| 10 | |
| 11 | == Bridging funds |
| 12 | |
| 13 | === K Long - discussion - slides ([raw-attachment:01-2024-02-20-Long.pptx here]) |
| 14 | |
| 15 | Bridging funds - discussion |
| 16 | |
| 17 | Deliverables |
| 18 | Work Package 1. Project management: Deliverables |
| 19 | |
| 20 | • '' D1 Early progress review CDR M6 '' |
| 21 | • '' D2 Interim progress review CDR M12 '' |
| 22 | • '' D3 Pre-CDR Review M18 '' |
| 23 | • '' D4 CDR M24 '' |
| 24 | |
| 25 | • ''' D5 Initial progress review TDR & technical de-risk update M30 ''' |
| 26 | • ''' D6 Interim progress review TDR & technical de-risk update M36 ''' |
| 27 | • ''' D7 Final progress review TDR & technical de-risk update M42 ''' |
| 28 | • ''' D8 Stage 1 TDR & technical de-risk report M48 ''' |
| 29 | |
| 30 | |
| 31 | • D9 Pre-TDR2 review M54 |
| 32 | • D10 TDR2 M60 |
| 33 | Milestones |
| 34 | |
| 35 | Work package 2: Laser-driven proton and ion source |
| 36 | |
| 37 | • ''' M2.3: Investigation and demonstration of 10 Hz debris and damage challenges at ICL M36 ''' |
| 38 | • ''' M2.4: Demonstration of continuous operation of 1 Hz beam generation on SCAPA M48 ''' |
| 39 | |
| 40 | Work package 3: Proton and ion capture |
| 41 | |
| 42 | |
| 43 | • ''' M3.3: Progress report on increased voltage penning trap simulations and operation. M36 ''' |
| 44 | • ''' M3.4: Final report high voltage penning trap operation. M48 ''' |
| 45 | |
| 46 | • M3.6: Ion focussing results M60 |
| 47 | |
| 48 | |
| 49 | === Radiobiological Science and technology |
| 50 | |
| 51 | Work Package 7: |
| 52 | |
| 53 | • ''' M7.1: Develop beamline and bespoke facilities at SCAPA for radiobiology experimentation M30 ''' |
| 54 | • ''' M7.2: Preliminary results from cell survival/DNA damage experiments with laser-accelerated protons at SCAPA M36 ''' |
| 55 | • ''' M7.3: Development of RBEs of laser-accelerated protons (versus pre-existing cyclotron-driven protons) in established cell lines M48 ''' |
| 56 | • ''' M7.4: Assessment of DNA damage repair kinetics and immunopeptidomic analysis of laser-accelerated protons M48 ''' |
| 57 | |
| 58 | Work package 4: Ion-acoustic dose mapping |
| 59 | |
| 60 | • ''' M4.3: Iterative reconstruction methods M42 ''' |
| 61 | • ''' M4.4: Integration: ultra-sonic array with radiobiology station M48 ''' may require manpower up-lift and some equipment funds |
| 62 | • ''' M4.5: LhARA ion-acoustic test results M48 ''' |
| 63 | |
| 64 | Work package 5: Novel end-station development |
| 65 | |
| 66 | • ''' M5.4: Construct transportable beam delivery end-station M42. ''' |
| 67 | • ''' M5.6: Report on LhARA stage 1 beam monitoring system M48. ''' |
| 68 | |
| 69 | |
| 70 | Work package 6: Design and integration |
| 71 | |
| 72 | • ''' M6.2: Final review of R&D work towards LhARA Phase 1 TDR M42 ''' |
| 73 | • ''' M6.3: Review of R&D work towards LhARA Phase 2 TDR M48 ''' |
| 74 | |
| 75 | Work Package 8: |
| 76 | |
| 77 | • ''' Creation of collaborative international clinical research group M40 ''' |
| 78 | • ''' Wider public engagement - All party parliamentary group on radiotherapy M48 ''' |
| 79 | |
| 80 | == PA1 |
| 81 | |
| 82 | === Achievements |
| 83 | |
| 84 | - humble bragg competition? |
| 85 | |
| 86 | === WP5 consultation 3, Jan 24th Liverpool. Excellent meeting |
| 87 | |
| 88 | https://indico.stfc.ac.uk/event/923/?print=1 |
| 89 | |
| 90 | |
| 91 | == AOB |