LhARA Project WPM Meeting 20th February 2024 14:00 GMT =

Meeting URL: ​​https://strath.zoom.us/j/84550543598?from=addon

Meeting ID: 845 5054 3598 Password: 737274

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Agenda

Bridging funds

K Long - discussion - slides (here)

Bridging funds - discussion

Deliverables Work Package 1. Project management: Deliverables

• D1 Early progress review CDR M6
• D2 Interim progress review CDR M12
• D3 Pre-CDR Review M18
• D4 CDR M24

• D5 Initial progress review TDR & technical de-risk update M30
• D6 Interim progress review TDR & technical de-risk update M36
• D7 Final progress review TDR & technical de-risk update M42
• D8 Stage 1 TDR & technical de-risk report M48

• D9 Pre-TDR2 review M54
• D10 TDR2 M60

Milestones

Work package 2: Laser-driven proton and ion source

• M2.3: Investigation and demonstration of 10 Hz debris and damage challenges at ICL M36
• M2.4: Demonstration of continuous operation of 1 Hz beam generation on SCAPA M48

Work package 3: Proton and ion capture

• M3.3: Progress report on increased voltage penning trap simulations and operation. M36
• M3.4: Final report high voltage penning trap operation. M48

• M3.6: Ion focussing results M60

Radiobiological Science and technology

Work Package 7:

• M7.1: Develop beamline and bespoke facilities at SCAPA for radiobiology experimentation M30
• M7.2: Preliminary results from cell survival/DNA damage experiments with laser-accelerated protons at SCAPA M36
• M7.3: Development of RBEs of laser-accelerated protons (versus pre-existing cyclotron-driven protons) in established cell lines M48
• M7.4: Assessment of DNA damage repair kinetics and immunopeptidomic analysis of laser-accelerated protons M48

Work package 4: Ion-acoustic dose mapping

• M4.3: Iterative reconstruction methods M42
• M4.4: Integration: ultra-sonic array with radiobiology station M48 may require manpower up-lift and some equipment funds
• M4.5: LhARA ion-acoustic test results M48

Work package 5: Novel end-station development

• M5.4: Construct transportable beam delivery end-station M42.
• M5.6: Report on LhARA stage 1 beam monitoring system M48.

Work package 6: Design and integration

• M6.2: Final review of R&D work towards LhARA Phase 1 TDR M42
• M6.3: Review of R&D work towards LhARA Phase 2 TDR M48

Work Package 8:

• Creation of collaborative international clinical research group M40
• Wider public engagement - All party parliamentary group on radiotherapy M48

PA1

Achievements

• humble bragg competition?

WP5 consultation 3, Jan 24th Liverpool. Excellent meeting

​https://indico.stfc.ac.uk/event/923/?print=1

AOB