BioPhysicsX meeting; 08Jun23; 08:00

Summary of actions:

• IMcN: Seek CSC seminar on LhARA intiative
• KL: Seek Amato om slides
• KL: Post set of presentations on wiki for reference and pilferring
• KL: Solicit or find slides from Yolanda
• CJ, KL, PP: Liaise to produce initial slide deck by 14Jun23
• IMcN: If there is a Div. of Cancer rep attending White City on 23Jun, make contact with
• KL: Seek meeting to brief Sandrine Heutz for KL and IMcN
• KL: (Added) Ask Sophie for slide template, if there is one

Notes

Present: IMcN, PP, CJ, KL.

1. Notes and actions: All
   Actions:
   • CJ, KL, PP to meet in a fortnight -- DONE
   • Seek two meetings with IMcN; one in a month and one just before his presentation on the 26Jun23 -- Done
   • IMcN: Consider seminar at CSC -- Stands

2. BioPhysicsX two-pager: CJ, All
   Present draft
   Points outstanding from last meeting:
   
   • Solicit input from:
     • Expert communicators.
     • European technology network, and, in consultation with IMcN, colleagues in FOM at Imperial.
   • Different versions need to be prepared for, e.g.:
     • "Public"/lay audience;
     • Influences/decision makers;
     • Funding agency personnel/Institute (Imperial, Oxford) leads
   We agreed:
   • Update to take into account PP comments;
   • Proceed to take advice on current draft as above;
   • Proceed to develop different versions for various audiences as above;
   • Add "pictures" where appropriate and add a timeline.

3. Support for IMcN 10 min presentation to CRUK on 26Jun23: CJ, All
   First draft of slides
   Key underlying messages, to help focus discussion:
   • improving clinical outcomes
   • radiobiology at cellular level, currently unchartered territory
   • innovation happens at disciplinary interfaces
   • already started
   • collaborative with international partners

Notes from our discussion:

• Need intro slide on science that will be addressed and why protons/ions are different to other sources of radiation. Need to emphasise, e.g.:
  • High LET; ions vs protons;
  • Flexibility of novel source; ion species, time, space, and energy distributions;
  • Different mechanisms for cell damage, different stimulation of immune response. Perhpas include "mean distance between ionising events" plot;
  • Mini/micro beams and biological excitement; (space and time structure of beam).
• Critical to get Amato i/p (action KL). Need to gather set of presentations on wiki for reference (action KL).
• Critical to get input from Yolanda and some of her slides (action KL).

5. CIO submission: KL, All
   Stalled again, will need biographical information for trustees ... take forward separately

• Under separate cover, liaise to get IMcN bio information (action KL).

6. Actions and next steps: All
   • We agreed:
     • Goal to get draft slides by 14Jun in advance of 16Jun meeting.
     • CJ, KL, PP will liaise.

7. DONM
   • 16Jun23; 08:00 BST

8. AoB
   • Note visit to White City: 23Jun23
     • IMcN will identify Div. of Cancer prepresentative so that KL and whomever can liaise.
   • Report to Sandrine Heutz
     • Agree KL will ask for a meeting to brief on our pitch.

Agenda

1. Notes and actions: All
   Actions:
   • CJ, KL, PP to meet in a fortnight -- DONE
   • Seek two meetings with IMcN; one in a month and one just before his presentation on the 26Jun23 -- Done
   • IMcN: Consider seminar at CSC

2. BioPhysicsX two-pager: CJ, All
   Present draft
   Points outstanding from last meeting:
   
   • Solicit input from:
     • Expert communicators.
     • European technology network, and, in consultation with IMcN, colleagues in FOM at Imperial.
   • Different versions need to be prepared for, e.g.:
     • "Public"/lay audience;
     • Influences/decision makers;
     • Funding agency personnel/Institute (Imperial, Oxford) leads

3. Support for IMcN 10 min presentation to CRUK on 26Jun23: CJ, All
   First draft of slides
   Key underlying messages, to help focus discussion:
   • improving clinical outcomes
   • radiobiology at cellular level, currently unchartered territory
   • innovation happens at disciplinary interfaces
   • already started
   • collaborative with international partners

5. CIO submission: KL, All
   Stalled again, will need biographical information for trustees ... take forward separately

6. Actions and next steps: All

7. DONM
   • 16Jun23; 08:00 BST

8. AoB
   • Note visit to White City: 23Jun23
   • Report to Sandrine Heutz

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