LhARA radiobiology; meeting: 05Feb26; 14:00 BST

ZOOM: ​https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1

Agenda

1. Minutes and actions completed:
   • AFr, DA: Write out RCF procedure document
     • DONE Awaiting Document
   • Unassigned (CD): Use sim to answer how many protons per shot in each fibre
     • DONE? Hopefully

2. In-Person Meeting

• Date: DECIDED 24th Feb at Birmingham
• Discussion on location
• Draft Agenda

3. SCAPA RW,ED:

• General Update

4. Bio EM,JP,MB:

• Actions Checklist
  • MB/EM: Send and evaluate the cells
  • EM, JMcG: Write up summary of PoPLaR Phase 2, including technical summary of cell irradiation procedure
  • EM: Share the counting software she uses with Marie
  • MB: Comet analysis
• General Updates

5. Beamline Diagnostic, KL, TP, CD, PH:

• Actions Checklist
  • EM/ED/LJ: Send calibration films to SCAPA and scan them in both orientations
  • AFr, DA: Write out RCF procedure document
    • DONE Awaiting Document
  • CD, TP: Evaluate LET in the cells with the RCF in front
  • Unassigned (CD): Use sim to answer how many protons per shot in each fibre
    • DONE? Hopefully
• General Updates

6. DoNM

• 19th Feb 14:00

7. AoB

Summary of actions required

Phase 2 Analysis

• EM, MB: Organise transport of cells to Birmingham for evaluation
• EM: Evaluate the cell results
• CD, AFr: Complete analysis of RCF with errors
• EM/ED/LJ: Send calibration films to SCAPA and scan them in both orientations
• EM, JMcG: Write up summary of PoPLaR Phase 2, including technical summary of cell irradiation procedure
• EM: Share the counting software she uses with Marie
• MB: Comet analysis

Beam Diagnostics

• AFr, DA: Write out RCF procedure document
• Unassigned: Find all the errors associated with RCF
• RW, CD: Study correlation between laser diagnostics and mean dose
• CD, TP: Evaluate LET in the cells with the RCF in front
• CD: Use sim to answer how many protons per shot in each fibre

Improve Bio results

• EM, JP: Discuss cell line to use next time?
• Unassigned: Obtain an inverted microscope

Long-term

• CD, JMcG: Investigate how to achieve uniformity without a scatterer in place
• KL, CW: Cost 4 or 6 quad, and chicane systems

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